Welcome to Guer Lab- Nanotech4Life

Our lab focus on the fabrication of DNA-assembled plasmonic nanostructures, optically active nanomaterial, dynamic DNA nanodevices, and their applications in biomedical research (biosensing, bioimaging) and nanomedicine.   

Our research direction include:

  • Nanobiophotonics, Plasmonics, and DNA Nanotechnology

  • Nanofabrication: Bottom-up synthesis of functional nanomaterials/nanostructures, self-assembled nanoprobes/nanodevices for biosensing & bioimaging

  • Physicochemical and optical characterization: Far/near-field advanced optical spectroscopies

The main objectives of our laboratory
  • Design and chemical synthesis of optical nanomaterials including metallic/bimetallic nanoparticles, polymeric nanoparticles, carbon-based nanomaterials, and quantum dots.
  • Surface chemistry: surface functionalization of optical nanomaterials after the synthesis for site-specific attachment. Surface functionalization includes single-stranded DNA conjugation for addressable binding, polymer conjugation for the stability of the particles, and biomolecule attachment (aptamers, proteins, antigen-antibody, and ligands) for targeted analyte detection.
  • DNA-based assembly: design and self-assembly of nanomaterials into functional optical nano systems/devices/robots/probes with nanometer precision. DNA nanotechnology allows us full control over the assembly and resulting in addressable and programmable nanodevice/nanoprobes.
  • Plasmonic and Optical systems: Nano antennas, Nano-probes, optical switches that change its conformation hence detection signal upon introducing single molecule (single molecule DNA/RNA detection).
  • The NanoBioPhotonic systems and devices in biomedical and energy applications:

          —Optical Biosensing (Raman sensing, Fluorescence sensing, surface plasmon resonance SPR sensing) 

          —Bioimaging (fluorescence and plasmonic-based cell/tissue imaging)

          —Energy conversion (plasmonic photocatalyst design)

JOIN US!

We’re currently looking for several highly motivated undergraduates, master students, PhD students, and postdocs. Please contact Dr. Fatih N. Gür fatih.guer@sjtu.edu.cn for more information.